Department of Chemistry and Biochemistry
Harper Cancer Research Institute
University of Notre Dame

Nishant K. Singh

Graduate Student

Nishant Kumar Singh is an advanced graduate student in the Baker Lab. He received his undergraduate degree at DePuaw University, with majors in Biochemistry and Biology. At DePauw, he worked as an undergraduate researcher in the department of Biochemistry for Dr. Dan Gurnon, where he worked on structural characterization of retro-viral protein Tax. After graduating from DePauw Nishant worked as a lab assistant at Medical College of Wisconsin in Dr. Jong-In Park’s Lab where he was responsible for developing a protocol of recombinant expression and purification of Leukimia Inhibitory Protein (LIF) from E.Coli.

Since joining Baker lab, he has been working on structural and biophysical characterization of several TCR variants with the goal to better understand the factors that govern affinity and specificity between TCRs and pMHCs partners. In general he is interested in understanding the thermodynamic basis of bimolecular interactions. He is highly passionate about cricket.