Department of Chemistry and Biochemistry
Harper Cancer Research Institute
University of Notre Dame

Lance M. Hellman, PhD

Research Scientist

Lance M Hellman is a postdoctoral fellow/research specialist in the lab. He earned his PhD from the University of Kentucky in Biochemistry and undergraduate BS degrees in Cytotechnology and Biology from the Medical University of South Carolina and the University of South Carolina respectively. Lance is originally from East Marion, NY but has lived in various places throughout the country including Alaska and South Carolina and he currently resides in Granger, IN with his family.

Lance’s main research focus is on structural-guided design of higher affinity T-cell receptors and their structural elucidation. He also works on various other projects/collaborations, including the determination of various biophysical properties of pMHC complexes. Lance employs a wide variety of techniques in his research, which include surface plasmon resonance, analytical ultracentrifugation, x-ray crystallography, fluorescence anisotropy, differential scanning fluorimetry, isothermal calorimetry, circular dichroism, and standard molecular biology techniques. Lance is especially interested in protein-protein interactions, protein-nucleic acid interactions, immunology, and the development of biophysical methods.

In his free time, Lance likes testing new cooking recipes and hiking in various places throughout the country. In the past he was also an avid rock climber. Lance loves the work he is doing in the lab and plans to stay at Notre Dame and continue working with Brian.